Pregabalin is a structural analogue of GABA that binds to the α2-δ subunit of voltage-gated calcium channels, reducing the release of excitatory neurotransmitters. It offers predictable linear pharmacokinetics and rapid onset of action across multiple neurological indications. Indicated for the treatment of peripheral and central neuropathic pain in adults, including diabetic peripheral neuropathy and post-herpetic neuralgia, as adjunctive therapy for partial-onset seizures, and for generalised anxiety disorder.